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Diagnostic and Therapeutic Strategies for Fluoropyrimidine Treatment of Patients Carrying Multiple DPYD Variants.
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Lunenburg CATC, Henricks LM, van Kuilenburg ABP, Mathijssen RHJ, Schellens JHM, Gelderblom H, Guchelaar HJ, Swen JJ
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30487465
|
28-11-2018
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06-05-2026
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Standard fluoropyrimidine dosages in chemoradiation therapy result in an increased risk of severe toxicity in DPYD variant allele carriers.
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Lunenburg CATC, Henricks LM, Dreussi E, Peters FP, Fiocco M, Meulendijks D, Toffoli G, Guchelaar HJ, Swen JJ, Cecchin E, Schellens JHM, Gelderblom H
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30361102
|
01-11-2018
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06-05-2026
|
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DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis.
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Henricks LM, Lunenburg CATC, de Man FM, Meulendijks D, Frederix GWJ, Kienhuis E, Creemers GJ, Baars A, Dezentjé VO, Imholz ALT, Jeurissen FJF, Portielje JEA, Jansen RLH, Hamberg P, Ten Tije AJ, Droogendijk HJ, Koopman M, Nieboer P, van de Poel MHW, Mandigers CMPW, Rosing H, Beijnen JH, Werkhoven EV, van Kuilenburg ABP, van Schaik RHN, Mathijssen RHJ, Swen JJ, Gelderblom H, Cats A, Guchelaar HJ, Schellens JHM
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30348537
|
01-11-2018
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06-05-2026
|
|
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Mass Spectrometric Identification of Cardiac Troponin T in Urine of Patients Suffering from Acute Myocardial Infarction.
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Streng AS, van der Linden N, Kocken JMM, Bekers O, Bouwman FG, Mariman ECM, Meex SJR, Wodzig WKWH, de Boer D
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33636816
|
01-05-2018
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14-04-2026
|
|
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Brain tissue plasticity: protein synthesis rates of the human brain.
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Smeets JSJ, Horstman AMH, Schijns OEMG, Dings JTA, Hoogland G, Gijsen AP, Goessens JPB, Bouwman FG, Wodzig WKWH, Mariman EC, van Loon LJC
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29432531
|
01-04-2018
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14-04-2026
|
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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update.
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Amstutz U, Henricks LM, Offer SM, Barbarino J, Schellens JHM, Swen JJ, Klein TE, McLeod HL, Caudle KE, Diasio RB, Schwab M
|
29152729
|
01-02-2018
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06-05-2026
|
|
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Capecitabine-based treatment of a patient with a novel DPYD genotype and complete dihydropyrimidine dehydrogenase deficiency.
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Henricks LM, Siemerink EJM, Rosing H, Meijer J, Goorden SMI, Polstra AM, Zoetekouw L, Cats A, Schellens JHM, van Kuilenburg ABP
|
28929491
|
15-01-2018
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06-05-2026
|
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Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial.
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Kouw IW, Holwerda AM, Trommelen J, Kramer IF, Bastiaanse J, Halson SL, Wodzig WK, Verdijk LB, van Loon LJ
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28855419
|
01-12-2017
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14-04-2026
|
|
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DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.
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Henricks LM, Opdam FL, Beijnen JH, Cats A, Schellens JHM
|
29045513
|
01-12-2017
|
06-05-2026
|
|
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Thrombin Activation via Serum Preparation Is Not the Root Cause for Cardiac Troponin T Degradation.
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Vroemen WHM, de Boer D, Streng AS, Bekers O, Wodzig WKWH
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28935651
|
01-11-2017
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14-04-2026
|
|
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Treatment Algorithm for Homozygous or Compound Heterozygous DPYD Variant Allele Carriers With Low-Dose Capecitabine.
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Henricks LM, Kienhuis E, de Man FM, van der Veldt AAM, Hamberg P, van Kuilenburg ABP, van Schaik RHN, Lunenburg CATC, Guchelaar HJ, Schellens JHM, Mathijssen RHJ
|
35172514
|
01-11-2017
|
06-05-2026
|
|
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Traceability in laboratory medicine: a global driver for accurate results for patient care.
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Beastall GH, Brouwer N, Quiroga S, Myers GL, prepared on behalf of the Joint Committee for Traceability in Laboratory Medicine
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28593871
|
26-07-2017
|
16-04-2026
|
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Food ingestion in an upright sitting position increases postprandial amino acid availability when compared with food ingestion in a lying down position.
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Holwerda AM, Lenaerts K, Bierau J, Wodzig WKWH, van Loon LJC
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28212491
|
01-07-2017
|
14-04-2026
|
|
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Large Variation in Measured Cardiac Troponin T Concentrations after Standard Addition in Serum or Plasma of Different Individuals.
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van der Linden N, Streng AS, Bekers O, Wodzig WKWH, Meex SJR, de Boer D
|
28536101
|
01-07-2017
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14-04-2026
|
|
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Letter regarding Zhao et al. entitled " DPYD gene polymorphisms are associated with risk and chemotherapy prognosis in pediatric patients with acute lymphoblastic leukemia".
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Deenen MJ, Henricks LM, Sonke GS, Schellens JH, Meulendijks D
|
28618970
|
01-06-2017
|
06-05-2026
|
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Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity.
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Meulendijks D, Henricks LM, Jacobs BAW, Aliev A, Deenen MJ, de Vries N, Rosing H, van Werkhoven E, de Boer A, Beijnen JH, Mandigers CMPW, Soesan M, Cats A, Schellens JHM
|
28427087
|
23-05-2017
|
06-05-2026
|
|
|
Identification and Characterization of Cardiac Troponin T Fragments in Serum of Patients Suffering from Acute Myocardial Infarction.
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Streng AS, de Boer D, van Doorn WP, Bouwman FG, Mariman EC, Bekers O, van Dieijen-Visser MP, Wodzig WK
|
27940450
|
01-02-2017
|
14-04-2026
|
|
|
Cardiac troponin T degradation in serum is catalysed by human thrombin.
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Streng AS, de Boer D, van Doorn WP, Kocken JM, Bekers O, Wodzig WK
|
27816455
|
02-12-2016
|
14-04-2026
|
|
|
Increasing Insulin Availability Does Not Augment Postprandial Muscle Protein Synthesis Rates in Healthy Young and Older Men.
|
Groen BB, Horstman AM, Hamer HM, de Haan M, van Kranenburg J, Bierau J, Poeze M, Wodzig WK, Rasmussen BB, van Loon LJ
|
27745529
|
01-11-2016
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14-04-2026
|
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Patients homozygous for DPYD c.1129-5923C>G/haplotype B3 have partial DPD deficiency and require a dose reduction when treated with fluoropyrimidines.
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Meulendijks D, Henricks LM, van Kuilenburg AB, Jacobs BA, Aliev A, Rozeman L, Meijer J, Beijnen JH, de Graaf H, Cats A, Schellens JH
|
27544765
|
01-10-2016
|
06-05-2026
|
|
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Development and validation of a rapid and sensitive UPLC-MS/MS method for determination of uracil and dihydrouracil in human plasma.
|
Jacobs BA, Rosing H, de Vries N, Meulendijks D, Henricks LM, Schellens JH, Beijnen JH
|
27179185
|
15-07-2016
|
06-05-2026
|
|
|
Physical Activity Performed in the Evening Increases the Overnight Muscle Protein Synthetic Response to Presleep Protein Ingestion in Older Men.
|
Holwerda AM, Kouw IW, Trommelen J, Halson SL, Wodzig WK, Verdijk LB, van Loon LJ
|
27281811
|
01-07-2016
|
14-04-2026
|
|
|
Rs895819 in MIR27A improves the predictive value of DPYD variants to identify patients at risk of severe fluoropyrimidine-associated toxicity.
|
Meulendijks D, Henricks LM, Amstutz U, Froehlich TK, Largiadèr CR, Beijnen JH, de Boer A, Deenen MJ, Cats A, Schellens JH
|
26804235
|
01-06-2016
|
06-05-2026
|
|
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Development of a targeted selected ion monitoring assay for the elucidation of protease induced structural changes in cardiac troponin T.
|
Streng AS, de Boer D, Bouwman FG, Mariman EC, Scholten A, van Dieijen-Visser MP, Wodzig WK
|
26772903
|
16-03-2016
|
14-04-2026
|
|
|
Validation, optimisation, and application data in support of the development of a targeted selected ion monitoring assay for degraded cardiac troponin T.
|
Streng AS, de Boer D, Bouwman FG, Mariman EC, Scholten A, van Dieijen-Visser MP, Wodzig WK
|
26977445
|
03-03-2016
|
14-04-2026
|
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