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Indirect determination of biochemistry reference intervals using outpatient data.
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Martinez-Sanchez L, Cobbaert CM, Noordam R, Brouwer N, Blanco-Grau A, Villena-Ortiz Y, Thelen M, Ferrer-Costa R, Casis E, Rodríguez-Frias F, den Elzen WPJ
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35588100
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19-05-2022
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16-04-2026
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Easy-to-Use HPLC Method to Measure Intracellular Ascorbic Acid Levels in Human Peripheral Blood Mononuclear Cells and in Plasma.
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van Gorkom G, Gijsbers B, Ververs EJ, El Molla A, Sarodnik C, Riess C, Wodzig W, Bos G, Van Elssen C
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35052638
|
07-01-2022
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14-04-2026
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Individualized Dosing of Fluoropyrimidine-Based Chemotherapy to Prevent Severe Fluoropyrimidine-Related Toxicity: What Are the Options?
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Knikman JE, Gelderblom H, Beijnen JH, Cats A, Guchelaar HJ, Henricks LM
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33020924
|
01-03-2021
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06-05-2026
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Cardiac Troponin T: The Impact of Posttranslational Modifications on Analytical Immunoreactivity in Blood up to the Excretion in Urine.
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de Boer D, Streng AS, van Doorn WPTM, Vroemen WHM, Bekers O, Wodzig WKWH, Mingels AMA
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33959905
|
01-01-2021
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14-04-2026
|
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Big data and reference intervals: rationale, current practices, harmonization and standardization prerequisites and future perspectives of indirect determination of reference intervals using routine data.
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Martinez-Sanchez L, Marques-Garcia F, Ozarda Y, Blanco A, Brouwer N, Canalias F, Cobbaert C, Thelen M, den Elzen W
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37359198
|
08-08-2020
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16-04-2026
|
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Biotin interference in high-sensitivity cardiac troponin T testing: a real-world evaluation in acute cardiac care.
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Vroemen WHM, van Doorn WPTM, Kimenai DM, Wodzig WKWH, de Boer D, Bekers O, Meex SJR
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31665256
|
01-12-2019
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14-04-2026
|
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Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial.
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Fuchs CJ, Hermans WJH, Holwerda AM, Smeets JSJ, Senden JM, van Kranenburg J, Gijsen AP, Wodzig WKHW, Schierbeek H, Verdijk LB, van Loon LJC
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31250889
|
01-10-2019
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14-04-2026
|
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Leucine coingestion augments the muscle protein synthetic response to the ingestion of 15 g of protein following resistance exercise in older men.
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Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig WKWH, Verdijk LB, de Groot LCPGM, van Loon LJC
|
31112406
|
01-09-2019
|
14-04-2026
|
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|
Multi-Site Coronary Vein Sampling Study on Cardiac Troponin T Degradation in Non-ST-Segment-Elevation Myocardial Infarction: Toward a More Specific Cardiac Troponin T Assay.
|
Damen SAJ, Vroemen WHM, Brouwer MA, Mezger STP, Suryapranata H, van Royen N, Bekers O, Meex SJR, Wodzig WKWH, Verheugt FWA, de Boer D, Cramer GE, Mingels AMA
|
31269858
|
16-07-2019
|
14-04-2026
|
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|
Effectiveness and safety of reduced-dose fluoropyrimidine therapy in patients carrying the DPYD*2A variant: A matched pair analysis.
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Henricks LM, van Merendonk LN, Meulendijks D, Deenen MJ, Beijnen JH, de Boer A, Cats A, Schellens JHM
|
30485432
|
01-05-2019
|
06-05-2026
|
|
|
DPYD genotype-guided dose individualisation of fluoropyrimidine therapy: who and how? - Authors' reply.
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Henricks LM, Lunenburg CATC, Cats A, Mathijssen RHJ, Guchelaar HJ, Schellens JHM
|
30712800
|
01-02-2019
|
06-05-2026
|
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|
Dose-Dependent Increases in Whole-Body Net Protein Balance and Dietary Protein-Derived Amino Acid Incorporation into Myofibrillar Protein During Recovery from Resistance Exercise in Older Men.
|
Holwerda AM, Paulussen KJM, Overkamp M, Goessens JPB, Kramer IF, Wodzig WKWH, Verdijk LB, van Loon LJC
|
30722014
|
01-02-2019
|
14-04-2026
|
|
|
A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy.
|
Henricks LM, Lunenburg CATC, de Man FM, Meulendijks D, Frederix GWJ, Kienhuis E, Creemers GJ, Baars A, Dezentjé VO, Imholz ALT, Jeurissen FJF, Portielje JEA, Jansen RLH, Hamberg P, Ten Tije AJ, Droogendijk HJ, Koopman M, Nieboer P, van de Poel MHW, Mandigers CMPW, Rosing H, Beijnen JH, van Werkhoven E, van Kuilenburg ABP, van Schaik RHN, Mathijssen RHJ, Swen JJ, Gelderblom H, Cats A, Guchelaar HJ, Schellens JHM
|
30544060
|
01-01-2019
|
06-05-2026
|
|
|
NUMBER: standardized reference intervals in the Netherlands using a 'big data' approach.
|
den Elzen WPJ, Brouwer N, Thelen MH, Le Cessie S, Haagen IA, Cobbaert CM
|
30218599
|
19-12-2018
|
16-04-2026
|
|
|
Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.
|
Henricks LM, Jacobs BAW, Meulendijks D, Pluim D, van den Broek D, de Vries N, Rosing H, Beijnen JH, Huitema ADR, Guchelaar HJ, Cats A, Schellens JHM
|
30047584
|
01-12-2018
|
06-05-2026
|
|
|
Diagnostic and Therapeutic Strategies for Fluoropyrimidine Treatment of Patients Carrying Multiple DPYD Variants.
|
Lunenburg CATC, Henricks LM, van Kuilenburg ABP, Mathijssen RHJ, Schellens JHM, Gelderblom H, Guchelaar HJ, Swen JJ
|
30487465
|
28-11-2018
|
06-05-2026
|
|
|
Standard fluoropyrimidine dosages in chemoradiation therapy result in an increased risk of severe toxicity in DPYD variant allele carriers.
|
Lunenburg CATC, Henricks LM, Dreussi E, Peters FP, Fiocco M, Meulendijks D, Toffoli G, Guchelaar HJ, Swen JJ, Cecchin E, Schellens JHM, Gelderblom H
|
30361102
|
01-11-2018
|
06-05-2026
|
|
|
DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis.
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Henricks LM, Lunenburg CATC, de Man FM, Meulendijks D, Frederix GWJ, Kienhuis E, Creemers GJ, Baars A, Dezentjé VO, Imholz ALT, Jeurissen FJF, Portielje JEA, Jansen RLH, Hamberg P, Ten Tije AJ, Droogendijk HJ, Koopman M, Nieboer P, van de Poel MHW, Mandigers CMPW, Rosing H, Beijnen JH, Werkhoven EV, van Kuilenburg ABP, van Schaik RHN, Mathijssen RHJ, Swen JJ, Gelderblom H, Cats A, Guchelaar HJ, Schellens JHM
|
30348537
|
01-11-2018
|
06-05-2026
|
|
|
Mass Spectrometric Identification of Cardiac Troponin T in Urine of Patients Suffering from Acute Myocardial Infarction.
|
Streng AS, van der Linden N, Kocken JMM, Bekers O, Bouwman FG, Mariman ECM, Meex SJR, Wodzig WKWH, de Boer D
|
33636816
|
01-05-2018
|
14-04-2026
|
|
|
Brain tissue plasticity: protein synthesis rates of the human brain.
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Smeets JSJ, Horstman AMH, Schijns OEMG, Dings JTA, Hoogland G, Gijsen AP, Goessens JPB, Bouwman FG, Wodzig WKWH, Mariman EC, van Loon LJC
|
29432531
|
01-04-2018
|
14-04-2026
|
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|
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update.
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Amstutz U, Henricks LM, Offer SM, Barbarino J, Schellens JHM, Swen JJ, Klein TE, McLeod HL, Caudle KE, Diasio RB, Schwab M
|
29152729
|
01-02-2018
|
06-05-2026
|
|
|
Capecitabine-based treatment of a patient with a novel DPYD genotype and complete dihydropyrimidine dehydrogenase deficiency.
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Henricks LM, Siemerink EJM, Rosing H, Meijer J, Goorden SMI, Polstra AM, Zoetekouw L, Cats A, Schellens JHM, van Kuilenburg ABP
|
28929491
|
15-01-2018
|
06-05-2026
|
|
|
Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial.
|
Kouw IW, Holwerda AM, Trommelen J, Kramer IF, Bastiaanse J, Halson SL, Wodzig WK, Verdijk LB, van Loon LJ
|
28855419
|
01-12-2017
|
14-04-2026
|
|
|
DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.
|
Henricks LM, Opdam FL, Beijnen JH, Cats A, Schellens JHM
|
29045513
|
01-12-2017
|
06-05-2026
|
|
|
Thrombin Activation via Serum Preparation Is Not the Root Cause for Cardiac Troponin T Degradation.
|
Vroemen WHM, de Boer D, Streng AS, Bekers O, Wodzig WKWH
|
28935651
|
01-11-2017
|
14-04-2026
|
|