Ascorbic acid serum levels are reduced in patients with hematological malignancies.
In this paper we demonstrate that patients treated with chemotherapy and/or hematopoietic stem cell transplantation (HSCT) have highly significant reduced serum ascorbic acid (AA) levels compared to healthy controls. We recently observed in in vitro experiments that growth of both T and NK cells from hematopoietic stem cells is positively influenced by AA. It might be of clinical relevance to study the function and recovery of immune cells after intensive treatment, its correlation to AA serum levels and the possible effect of AA supplementation.
Auteur(s)
Huijskens MJ, Wodzig WK, Walczak M, Germeraad WT, Bos GM
PubMed nr.
Tijdschrift
Results in immunology
Datum publicatie
12-01-2016
Datum toegevoegd
14-04-2026
Toegevoegd door