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Project 286 Extracellular vesicles for drug delivery
Onderzoekslijn Nanomedicine
Omschrijving Extracellular vesicles (EVs) are nanoparticles, 30-1000 nm in size, with an aqueous core and phospholipid membranes. They are produced by cells particularly when cells are activated. More recently, the discovery that they contain selected RNAs and proteins that can be transferred from one cell to another suggests a new form of long distance intercellular communication.Our lab studies EVs as potential drug carriers. We develop methods for large scale EV isolation, investigate tools for drug loading and design novel ways to achieve cell targeting. In addition, we aim to characterize EV components important for uptake and processing by target cells, in order to improve synthetic drug delivery systems through EV-inspired engineering.
Projectleider Prof.dr. W.W.(Wouter) van Solinge
Instituut Universitair Medisch Centrum Utrecht locatie AZU Utrecht
Trefwoorden
Status Lopend
Periode 1-2010 - 1-2024
Partners
Medewerkers Dr Pieter Vader
Olivier de Jong
Sander Kooijmans
Susan van Dommelen
Linglei Jiang
Jerney Gitz
Sandra Drost
Financiering 3e Geldstroom - Subsidies, fondsen (incl. EU)

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